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Health and Diseases » Thrombosis

Iliac vein stenosis increases left-sided deep vein thrombosis (DVT) risk in women used combined oral contraceptive (COC)

Up to 25% of people in the healthy population have underlying stenosis for greater than 50% of the left common iliac vein. However, for women who have significant venous stenosis of the common iliac vein, who also use combined oral contraceptives (COC), they are at higher risk of deep vein thrombosis (DVT) than average risk. According to recent findings, every 1% increase in iliac vein stenosis (greater than 70%) increased the risk of DVT by 5%. And those who also use COC, the odds ratio of DVT increase to 5.46% for every 1% increase in stenosis. This conclusion based on evaluated 35 DVT’s women with computed tomography or magnetic resonance imaging and 35 age-matched control women who presented to the emergency room with abdominal pain. Reported in the American Journal of Obstetrics and Gynecology … Read entire article »

Filed under: Thrombosis

Subcutaneous heparin not optimal protect against venous thromboembolism (VTE) prophylaxis than intravenous heparin to patients undergone abdominal surgery

Currently, standard care for blood clot that forms within a vein or venous thromboembolism (VTE) is by subcutaneous heparin. However, current findings that presented at the Society of Critical Care Medicine 40th Critical Care Congress, patients that received subcutaneous heparin no better than intravenous (IV) heparin protects against VTE. According to the authors of the study, the patients who have undergone major abdominal surgery had no detectable levels of anti-Xa activity 5 days after surgery (the peak levels of anti-Xa activity were 0), because absorption appears to be decreased in these patients. But, those received IV heparin showed statistically significant increases in anti-Xa activity on day 3 and day 4, although the levels are still low (0.04 U/mL in day 3, and 0.05 U/mL in day 4). Also, by using a whole blood … Read entire article »

Filed under: Thrombosis